chemistryRP6 · Chemical AnalysisPaper 2Combined and Separate

Paper chromatography

Method overview

Draw a pencil baseline, place small concentrated spots, stand paper in solvent below the baseline, cover, allow solvent to rise, remove before the top, mark solvent front immediately, dry and calculate Rf.

Apparatus set-up

Diagram
Solvent chamber (lid on)
Capillary tube spots dye
Measure Rf value

chromatography paper; pencil; ruler; capillary tubes; solvent; beaker with lid; reference dyes

Independent variable

sample identity or solvent

Dependent variable

number/position of spots and Rf values

Control variables

baseline height; solvent depth; paper; temperature; spot size

Apparatus

chromatography paper; pencil; ruler; capillary tubes; solvent; beaker with lid; reference dyes

Safety

Wear eye protection; some solvents are flammable/irritant; use ventilation and no flames.

Scientific rationale

Pencil is insoluble; baseline must be above solvent; lid reduces evaporation; components separate because of different affinities for mobile and stationary phases.

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